Brief Information of the Compound and Protein
Compound Name
benzyl 3-(3-(3,4-difluorobenzyl)-2-oxotetrahydropyrimidin-1(2H)-yl)phenylcarbamate
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PubChem ID
CID: 46040695
Canonical SMILES
O=C(Nc1cccc(N2CCCN(Cc3ccc(F)c(F)c3)C2=O)c1)OCc1ccccc1
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Compound Formula C25H23F2N3O3
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 1200 nM
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