Brief Information of the Compound and Protein
Compound Name
4-fluoro-N-(2-(2-(4-fluorophenyl)quinazolin-4-ylamino)ethyl)-2-methoxybenzenesulfonamide
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PubChem ID
CID: 83284521
Canonical SMILES
COc1cc(F)ccc1S(=O)(=O)NCCNc1nc(-c2ccc(F)cc2)nc2ccccc12
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Compound Formula C23H20F2N4O3S
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 > 10000 nM
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