Brief Information of the Compound and Protein
Compound Name
10-{3-[4-(2-Fluoro-phenyl)-piperazine-1-carbonyl]-phenyl}-6-methoxy-9-methyl-8-oxa-10,12-diaza-tricyclo[7.3.1.0(2,7)]trideca-2(7),3,5-trien-11-one
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PubChem ID
CID: 15995252
Canonical SMILES
COc1cccc2c1OC1(C)CC2NC(=O)N1c1cccc(C(=O)N2CCN(c3ccccc3F)CC2)c1
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Compound Formula C29H29FN4O4
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
P56726
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 > 10000 nM
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