Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(2-methylpropyl)sulfonamido]-3-hydroxy-1-phenylbutan-2-yl]carbamate
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 PubChem ID
CID: 213039
SID: 12015589
Canonical SMILES
CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc(N)cc1
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Compound Formula C27H37N3O7S
Compound Structure
Protein Name
 Protein Info 
Protease
Protein Classification
Enzyme
>
Protease
>
Cysteine protease
>
Cysteine protease PAC clan
>
Cysteine protease C3A subfamily
Uniprot ID
Q9YQ12
Gene Name
PROTEASE
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 12.66 nM
   TI
   LI
   LO
   TS
2
EC50 = 112.08 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.8 nM
2 Kd = 0.016 nM
3 Ki = 0.01 nM
4 Ki = 0.014 nM
5 Ki = 0.016 nM
6 Ki = 0.34 nM
7 Ki = 0.5 nM
8 Ki = 9 nM
9 Ki = 18 nM
10 Ki = 22 nM