Brief Information of the Compound and Protein
Compound Name
3,4-difluoro-N-[5-[5-(2-methyl-1-oxo-3H-isoindol-5-yl)thiophen-2-yl]pyridin-3-yl]benzenesulfonamide
    Show/Hide
PubChem ID
CID: 73297191
Canonical SMILES
CN1Cc2cc(ccc2C1=O)-c1ccc(s1)-c1cncc(NS(=O)(=O)c2ccc(F)c(F)c2)c1
    Show/Hide
Compound Formula C24H17F2N3O3S2
Compound Structure
Protein Name
Perforin-1
Protein Classification
Ion channel
>
Other ion channel
>
Pore-forming toxins (proteins and peptides)
Uniprot ID
P14222
Gene Name
PRF1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 18600 nM
   TI
   LI
   LO
   TS