Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[2-[(2-chloro-6-fluorophenyl)methoxy]ethylsulfanyl]-5-[2-(3,4-dichlorophenyl)propan-2-yl]-1-(4-fluorophenyl)imidazole
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 PubChem ID
CID: 89501664
Canonical SMILES
CC(C)(c1cnc(SCCOCc2c(F)cccc2Cl)n1-c1ccc(F)cc1)c1ccc(Cl)c(Cl)c1
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Compound Formula C27H23Cl3F2N2OS
Compound Structure
Protein Name
 Protein Info 
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 35.7 nM
   TI
   LI
   LO
   TS