Brief Information of the Compound and Protein
Compound Name
5-[4-(tert-butylsulfamoyl)naphthalen-1-yl]-4-(cyclohexylmethyl)-N-[(4-ethylsulfonylphenyl)methyl]-1,3-thiazole-2-carboxamide
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PubChem ID
CID: 145961622
Canonical SMILES
CCS(=O)(=O)c1ccc(CNC(=O)c2nc(CC3CCCCC3)c(s2)-c2ccc(c3ccccc23)S(=O)(=O)NC(C)(C)C)cc1
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Compound Formula C34H41N3O5S3
Compound Structure
Protein Name
Nuclear receptor ROR-beta
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
Uniprot ID
Q92753
Gene Name
RORB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 13 nM
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