Brief Information of the Compound and Protein
Compound Name
4-cyclohexyl-5-[2,3-dichloro-4-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]phenyl]-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide
    Show/Hide
PubChem ID
CID: 118186179
Canonical SMILES
C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2C2CCCCC2)C(=O)NCC(C)(C)O)c(Cl)c1Cl)C(F)(F)F
    Show/Hide
Compound Formula C23H28Cl2F3N3O4S2
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group F
>
Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS