Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-tert-butyl-4-[4-(cyclohexylmethyl)-2-(7,7-dioxo-7lambda6-thia-2-azaspiro[3.5]nonane-2-carbonyl)-1,3-thiazol-5-yl]naphthalene-1-sulfonamide
    Show/Hide
 PubChem ID
CID: 118185666
Canonical SMILES
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)N2CC3(C2)CCS(=O)(=O)CC3)c2ccccc12
    Show/Hide
Compound Formula C32H41N3O5S3
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group F
>
Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 8.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 906 nM