Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(cyclopropylmethyl)-N-(1,1-dioxothian-4-yl)-5-[4-[[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl]naphthalen-1-yl]-1,3-thiazole-2-carboxamide
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 PubChem ID
CID: 145961343
Canonical SMILES
C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CC2)C(=O)NC2CCS(=O)(=O)CC2)c2ccccc12)C(F)(F)F
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Compound Formula C26H28F3N3O5S3
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 6.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 58 nM