Brief Information of the Compound and Protein
Compound Name
(R)-5-(1-(1-((5-chloropyridin-2-yl)methyl)piperidin-4-yl)propyl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-4-methylthiophene-3-carboxamide
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PubChem ID
CID: 145961928
Canonical SMILES
CC[C@@H](c1scc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCN(Cc2ccc(Cl)cn2)CC1
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Compound Formula C28H35ClN4O2S
Compound Structure
Protein Name
Histone-lysine N-methyltransferase EZH2
Protein Classification
Epigenetic regulator
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Protein methyltransferase
Uniprot ID
Q15910
Gene Name
EZH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 <= 10 nM
   TI
   LI
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   TS