Brief Information of the Compound and Protein
Compound Name
2-[1-hydroxy-4-[[4-(trifluoromethyl)phenyl]methyl]cyclohexyl]-N-(2-oxo-3H-1,3-benzoxazol-6-yl)acetamide
    Show/Hide
Canonical SMILES
O[C@]1(CC(=O)Nc2ccc3[nH]c(=O)oc3c2)CC[C@H](Cc2ccc(cc2)C(F)(F)F)CC1
    Show/Hide
Compound Formula C23H23F3N2O4
Compound Structure
Protein Name
Glutamate receptor ionotropic, NMDA 2B
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
Ionotropic glutamate receptor
>
NMDA receptor
Uniprot ID
Q01097
Gene Name
GRIN2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 6.31 nM
   TI
   LI
   LO
   TS