Brief Information of the Compound and Protein
Compound Name
3-N-[4-[4-(2-bicyclo[2.2.1]heptanyl)piperazin-1-yl]-3-chlorophenyl]-1-thieno[2,3-d]pyrimidin-4-yl-1,2,4-triazole-3,5-diamine
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PubChem ID
CID: 77631108
Canonical SMILES
Nc1nc(Nc2ccc(N3CCN(CC3)C3CC4CCC3C4)c(Cl)c2)nn1-c1ncnc2sccc12
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Compound Formula C25H28ClN9S
Compound Structure
Protein Name
Tyrosine-protein kinase receptor UFO
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Axl family
Uniprot ID
P30530
Gene Name
AXL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 85 nM
   TI
   LI
   LO
   TS