Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbonyl]-4-fluorophenyl}methyl)-1,2-dihydrophthalazin-1-one
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 PubChem ID
CID: 23725625
SID: 85197660
Canonical SMILES
Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCN(CC1)C(=O)C1CC1
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Compound Formula C24H23FN4O3
Compound Structure
Protein Name
 Protein Info 
Poly [ADP-ribose] polymerase 2
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q9UGN5
Gene Name
PARP2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 0.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.81 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.1 nM
2 IC50 = 0.4 nM
3 IC50 = 0.45 nM
4 IC50 = 1 nM
5 IC50 = 1.01 nM
6 IC50 = 1.2 nM
7 IC50 = 1.87 nM
8 IC50 = 2.26 nM
9 IC50 = 2.81 nM
10 IC50 = 2.93 nM
11 IC50 = 3 nM
12 Kd = 0.27 nM
13 Kd = 0.28 nM
14 Kd = 0.5 nM