Brief Information of the Compound and Protein
Compound Name
6-(4-aminophenyl)-8-(3-bromo-4,5-dihydro-1,2-oxazol-5-yl)-3,10-dihydro-2H-[1,4]dioxino[2,3-h][2,3]benzodiazepin-9-one
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PubChem ID
CID: 137660839
Canonical SMILES
Nc1ccc(cc1)C1=NN(C2CC(Br)=NO2)C(=O)Cc2cc3OCCOc3cc12
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Compound Formula C20H17BrN4O4
Compound Structure
Protein Name
Glutamate receptor 2
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
Ionotropic glutamate receptor
>
AMPA receptor
Uniprot ID
P42262
Gene Name
GRIA2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
Ki = 3000 nM
   TI
   LI
   LO
   TS
2
Ki = 14000 nM
   TI
   LI
   LO
   TS