Brief Information of the Compound and Protein
Compound Name
4-(((4-((4-(4-Cyano-2,6-dimethylphenoxy)thieno[3,2-d]pyrimidin-2-yl)amino)cyclohexyl)amino)methyl)benzenesulfonamide
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PubChem ID
CID: 129909050
Canonical SMILES
Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCC(NCc3ccc(S(N)(=O)=O)cc3)CC2)nc2ccsc12
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Compound Formula C28H30N6O3S2
Compound Structure
Protein Name
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
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Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4 Homo sapiens (Human)  3
1
EC50 = 152 nM
   TI
   LI
   LO
   TS
2
EC50 = 175 nM
   TI
   LI
   LO
   TS
3
EC50 > 3690 nM
   TI
   LI
   LO
   TS