Brief Information of the Compound and Protein
Compound Name
Ethyl4-((4-(4-Cyano-2,6-dimethylphenoxy)thieno[3,2-d]-pyrimidin-2-yl)amino)-1-(4-sulfamoylbenzyl)piperidine-3-carboxylate
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PubChem ID
CID: 129909746
Canonical SMILES
CCOC(=O)C1CN(Cc2ccc(S(N)(=O)=O)cc2)CCC1Nc1nc(Oc2c(C)cc(C#N)cc2C)c2sccc2n1
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Compound Formula C30H32N6O5S2
Compound Structure
Protein Name
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4 Homo sapiens (Human)  7
1
EC50 = 186 nM
   TI
   LI
   LO
   TS
2
EC50 = 239 nM
   TI
   LI
   LO
   TS
3
EC50 = 389 nM
   TI
   LI
   LO
   TS
4
EC50 = 607 nM
   TI
   LI
   LO
   TS
5
EC50 = 1270 nM
   TI
   LI
   LO
   TS
6
EC50 >= 918 nM
   TI
   LI
   LO
   TS
7
EC50 > 4248 nM
   TI
   LI
   LO
   TS