Brief Information of the Compound and Protein
Compound Name
4-((2-((4-(benzylamino)cyclohexyl)amino)thieno[3,2-d]pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile
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PubChem ID
CID: 129908982
Canonical SMILES
Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCC(NCc3ccccc3)CC2)nc2ccsc12
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Compound Formula C28H29N5OS
Compound Structure
Protein Name
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4 Homo sapiens (Human)  5
1
EC50 = 754 nM
   TI
   LI
   LO
   TS
2
EC50 = 891 nM
   TI
   LI
   LO
   TS
3
EC50 = 983 nM
   TI
   LI
   LO
   TS
4
EC50 = 1050 nM
   TI
   LI
   LO
   TS
5
EC50 > 2980 nM
   TI
   LI
   LO
   TS