Brief Information of the Compound and Protein
Compound Name
[(4aR,8aS)-1-(4-fluorophenyl)-6-[3-(trifluoromethyl)phenyl]sulfonyl-4,5,7,8,8a,9-hexahydropyrazolo[3,4-g]isoquinolin-4a-yl]-pyridin-2-ylmethanone
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PubChem ID
CID: 118092345
Canonical SMILES
Fc1ccc(cc1)-n1ncc2C[C@@]3(CN(CC[C@H]3Cc12)S(=O)(=O)c1cccc(c1)C(F)(F)F)C(=O)c1ccccn1
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Compound Formula C29H24F4N4O3S
Compound Structure
Protein Name
Glucocorticoid receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
Ki = 44 nM
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