Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-methyl-1-(3-morpholin-4-ylpropyl)-5-phenyl-N-[3-(trifluoromethyl)phenyl]pyrrole-3-carboxamide
    Show/Hide
 PubChem ID
CID: 2742550
Canonical SMILES
Cc1c(cc(-c2ccccc2)n1CCCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F
    Show/Hide
Compound Formula C26H28F3N3O2
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily V member 4
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Transient receptor potential channel
Uniprot ID
Q9HBA0
Gene Name
TRPV4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
2
IC50 = 57 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 48 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 18 nM
2 IC50 = 48 nM
3 IC50 = 57 nM