Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[6-[[3-(1,3-dimethylpyrazol-4-yl)-1,2,4-thiadiazol-5-yl]amino]pyridin-3-yl]-[3-[5-(trifluoromethyl)pyrimidin-2-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone
    Show/Hide
 PubChem ID
CID: 137650754
Canonical SMILES
Cc1nn(C)cc1-c1nsc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(cn2)C(F)(F)F)n1
    Show/Hide
Compound Formula C24H23F3N10OS
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily V member 4
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Transient receptor potential channel
Uniprot ID
Q9HBA0
Gene Name
TRPV4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 6.2 nM
   TI
   LI
   LO
   TS