Brief Information of the Compound and Protein
Compound Name
(2R)-N'-(5-fluoro-2-methylpyridin-3-yl)-2-methyl-N-[(6S)-5-oxo-2,3,6,11-tetrahydro-1H-pyrazolo[1,2-b][2,3]benzodiazepin-6-yl]butanediamide
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PubChem ID
CID: 137650478
Canonical SMILES
C[C@H](CC(=O)Nc1cc(F)cnc1C)C(=O)N[C@H]1c2ccccc2CN2CCCN2C1=O
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Compound Formula C23H26FN5O3
Compound Structure
Protein Name
Signal peptide peptidase-like 2A
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9JJF9
Gene Name
SPPL2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000160 A20 Mus musculus (Mouse)  1
1
IC50 = 97 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 50 nM