Brief Information of the Compound and Protein
Compound Name
2-[(4-nitrophenyl)carbamoylamino]-N-[4-(trifluoromethyl)phenyl]benzamide
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PubChem ID
CID: 137637400
Canonical SMILES
[O-][N+](=O)c1ccc(NC(=O)Nc2ccccc2C(=O)Nc2ccc(cc2)C(F)(F)F)cc1
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Compound Formula C21H15F3N4O4
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000836 H460/MX20 Homo sapiens (Human)  3
1
IC50 = 452 nM
   TI
   LI
   LO
   TS
2
IC50 = 605 nM
   TI
   LI
   LO
   TS
3
IC50 = 711 nM
   TI
   LI
   LO
   TS