Brief Information of the Compound and Protein
Compound Name
4-amino-N-[2-[2-(3-methoxyphenyl)tetrazol-5-yl]phenyl]benzamide
    Show/Hide
PubChem ID
CID: 137652882
Canonical SMILES
COc1cccc(c1)-n1nnc(n1)-c1ccccc1NC(=O)c1ccc(N)cc1
    Show/Hide
Compound Formula C21H18N6O2
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000836 H460/MX20 Homo sapiens (Human)  3
1
IC50 = 299 nM
   TI
   LI
   LO
   TS
2
IC50 = 491 nM
   TI
   LI
   LO
   TS
3
IC50 = 549 nM
   TI
   LI
   LO
   TS