Brief Information of the Compound and Protein
Compound Name
1-(4-methoxyphenyl)-3-[2-[2-(4-methoxyphenyl)tetrazol-5-yl]phenyl]urea
    Show/Hide
PubChem ID
CID: 137649297
Canonical SMILES
COc1ccc(NC(=O)Nc2ccccc2-c2nnn(n2)-c2ccc(OC)cc2)cc1
    Show/Hide
Compound Formula C22H20N6O3
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000836 H460/MX20 Homo sapiens (Human)  3
1
IC50 = 355 nM
   TI
   LI
   LO
   TS
2
IC50 = 382 nM
   TI
   LI
   LO
   TS
3
IC50 = 442 nM
   TI
   LI
   LO
   TS