Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[(2R,3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-acetylpyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-[3-[8-(2-fluoro-6-phenoxyphenyl)octyl]imidazol-4-yl]propanoyl]amino]-3-hydroxypropanoyl]amino]-4-amino-4-oxobutan-2-yl] dihydrogen phosphate
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 PubChem ID
CID: 134143682
Canonical SMILES
CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1c(F)cccc1Oc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)OP(O)(O)=O)C(N)=O
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Compound Formula C46H66FN8O12P
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase PLK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase PLK family
Uniprot ID
P53350
Gene Name
PLK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 6.6 nM
   TI
   LI
   LO
   TS
2
IC50 = 66 nM
   TI
   LI
   LO
   TS
3
IC50 = 127 nM
   TI
   LI
   LO
   TS