Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butylboronic acid
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 PubChem ID
CID: 387447
SID: 14853748
Canonical SMILES
CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O
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Compound Formula C19H25BN4O4
Compound Structure
Protein Name
 Protein Info 
Proteasome subunit beta type-1
Protein Classification
Enzyme
>
Protease
>
Threonine protease
>
Threonine protease PBT clan
>
Threonine protease T1A subfamily
Uniprot ID
P20618
Gene Name
PSMB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 19 nM
2 IC50 = 53 nM
3 IC50 = 70 nM
4 IC50 = 90 nM
5 IC50 = 96.5 nM
6 IC50 = 104 nM
7 IC50 = 130 nM
8 IC50 = 296.7 nM
9 IC50 = 700 nM