Brief Information of the Compound and Protein
Compound Name
6-chloro-2-(4-chloropyridin-2-yl)-N-[(4-methoxyphenyl)methyl]imidazo[1,2-a]pyridin-3-amine
    Show/Hide
PubChem ID
CID: 137650941
Canonical SMILES
COc1ccc(CNc2c(nc3ccc(Cl)cn23)-c2cc(Cl)ccn2)cc1
    Show/Hide
Compound Formula C20H16Cl2N4O
Compound Structure
Protein Name
Bile acid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group H
>
Nuclear hormone receptor subfamily 1 group H member 4
Uniprot ID
Q96RI1
Gene Name
NR1H4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 0.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 37 nM