Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CHEMBL4063313
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Canonical SMILES
O[C@@]1(CC[C@@H](CC1)Nc1ccc(cc1Cl)-c1ccn2c(CC3CC3)nnc2c1C(F)(F)F)C1CC1
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Compound Formula C26H28ClF3N4O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
EC50 = 1.122 nM
   TI
   LI
   LO
   TS
2
EC50 = 11.22 nM
   TI
   LI
   LO
   TS
3
Kd = 1.5 nM
   TI
   LI
   LO
   TS
4
Ki = 0.8913 nM
   TI
   LI
   LO
   TS