Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-chloro-4-[3-(cyclopropylmethyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl]-N-propan-2-ylaniline
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 PubChem ID
CID: 66785300
Canonical SMILES
CC(C)Nc1ccc(cc1Cl)-c1ccn2c(CC3CC3)nnc2c1C(F)(F)F
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Compound Formula C20H20ClF3N4
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 17.38 nM
   TI
   LI
   LO
   TS
2
Kd = 3.4 nM
   TI
   LI
   LO
   TS
3
Ki = 3.89 nM
   TI
   LI
   LO
   TS