Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-chloro-3-(cyclopropylmethyl)-7-[3-fluoro-4-(2-methylpyridin-4-yl)oxyphenyl]-[1,2,4]triazolo[4,3-a]pyridine
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 PubChem ID
CID: 49801371
SID: 103773135
Canonical SMILES
Cc1cc(Oc2ccc(cc2F)-c2ccn3c(CC4CC4)nnc3c2Cl)ccn1
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Compound Formula C22H18ClFN4O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 251.19 nM
   TI
   LI
   LO
   TS
2
Kd = 37.6 nM
   TI
   LI
   LO
   TS
3
Ki = 63.1 nM
   TI
   LI
   LO
   TS