Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[[4-[[3-hydroxy-4-(2-methylpropanoyl)-2-(trifluoromethyl)phenoxy]methyl]phenyl]methyl]-1-methylimidazole-4-carboxamide
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 PubChem ID
CID: 44595851
SID: 87328101
Canonical SMILES
CC(C)C(=O)c1ccc(OCc2ccc(CNC(=O)c3cn(C)cn3)cc2)c(c1O)C(F)(F)F
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Compound Formula C24H24F3N3O4
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 107.15 nM
   TI
   LI
   LO
   TS
2
Kd = 100 nM
   TI
   LI
   LO
   TS
3
Ki = 79.43 nM
   TI
   LI
   LO
   TS