Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-N-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine
    Show/Hide
 PubChem ID
CID: 73389731
Canonical SMILES
Nc1nc(NC2CC2)cc(n1)-c1cccc(Cl)c1Cl
    Show/Hide
Compound Formula C13H12Cl2N4
Compound Structure
Protein Name
 Protein Info 
Oxidized purine nucleoside triphosphate hydrolase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
P36639
Gene Name
NUDT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000002 K-562
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
2
EC50 = 125.89 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM
2 IC50 = 5 nM
3 IC50 = 7 nM
4 IC50 = 10 nM
5 Kd = 5 nM