Brief Information of the Compound and Protein
Compound Name
(2S)-2-amino-4-[[(4-fluoro-3-nitrophenyl)-hydroxymethyl]-hydroxyphosphoryl]butanoic acid
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PubChem ID
CID: 57765613
Canonical SMILES
N[C@@H](CCP(O)(=O)C(O)c1ccc(F)c(c1)[N+]([O-])=O)C(O)=O
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Compound Formula C11H14FN2O7P
Compound Structure
Protein Name
Metabotropic glutamate receptor 8
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
O00222
Gene Name
GRM8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 660 nM
   TI
   LI
   LO
   TS
2
EC50 = 1300 nM
   TI
   LI
   LO
   TS