Brief Information of the Compound and Protein
Compound Name
N-[(1R,2S)-1-[(2R,5R)-5-(cyclohexylmethoxy)piperidin-2-yl]-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl]acetamide;hydrochloride
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PubChem ID
CID: 137637305
Canonical SMILES
Cl.CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)[C@H]1CC[C@H](CN1)OCC1CCCCC1
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Compound Formula C23H35ClF2N2O3
Compound Structure
Protein Name
Beta-secretase 1
Protein Classification
Enzyme
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Protease
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Aspartic protease
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Aspartic protease AA clan
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Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 1320 nM
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