Brief Information of the Compound and Protein
Compound Name
2-[(7-oxo-5-phenyl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]acetic acid
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Canonical SMILES
OC(=O)CNC(=O)c1cnn2c(O)cc(nc12)-c1ccccc1
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Compound Formula C15H12N4O4
Compound Structure
Protein Name
Cyclic GMP-AMP synthase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8N884
Gene Name
CGAS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 10600 nM
   TI
   LI
   LO
   TS
2
IC50 = 21000 nM
   TI
   LI
   LO
   TS
3
Kd = 6700 nM
   TI
   LI
   LO
   TS