Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-4-oxo-6-propoxy-1,4-dihydroquinoline-2-carboxylic acid
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 PubChem ID
CID: 25211074
SID: 57552611
Canonical SMILES
CCCOc1ccc2n(Cc3cc4OCOc4cc3CC)c(C(O)=O)c(Cc3cccc(c3)C(O)=O)c(=O)c2c1
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Compound Formula C31H29NO8
Compound Structure
Protein Name
 Protein Info 
Endothelin-1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P25101
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 4.2 nM
   TI
   LI
   LO
   TS
CL000057 Vero
 Cell Line Info 
Chlorocebus sabaeus (Green monkey)  1
1
IC50 = 0.11 nM
   TI
   LI
   LO
   TS