Brief Information of the Compound and Protein
Compound Name
6-ethoxy-1-[(6-ethyl-1,3-benzodioxol-5-yl)methyl]-4-oxo-3-[[3-(2H-tetrazol-5-yl)phenyl]methyl]quinoline-2-carboxylic acid
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PubChem ID
CID: 137642741
Canonical SMILES
CCOc1ccc2n(Cc3cc4OCOc4cc3CC)c(C(O)=O)c(Cc3cccc(c3)-c3nnn[nH]3)c(=O)c2c1
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Compound Formula C30H27N5O6
Compound Structure
Protein Name
Endothelin receptor type B
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P24530
Gene Name
EDNRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 4072.1 nM
   TI
   LI
   LO
   TS