Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3S)-3-[4-[[4-(spiro[indene-1,4'-piperidine]-1'-ylmethyl)phenyl]methoxy]phenyl]hex-4-ynoic acid
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 PubChem ID
CID: 51049992
SID: 118044310
Canonical SMILES
CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(CN3CCC4(CC3)C=Cc3ccccc43)cc2)cc1
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Compound Formula C33H33NO3
Compound Structure
Protein Name
 Protein Info 
Free fatty acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  5
1
EC50 = 1.2 nM
   TI
   LI
   LO
   TS
2
EC50 = 8.7 nM
   TI
   LI
   LO
   TS
3
EC50 = 9.1 nM
   TI
   LI
   LO
   TS
4
EC50 = 134 nM
   TI
   LI
   LO
   TS
5
Ki = 4.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 233 nM