Brief Information of the Compound and Protein
Compound Name
(3S)-3-[4-[[2-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-6-yl]methoxy]phenyl]hex-4-ynoic acid
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PubChem ID
CID: 118129974
Canonical SMILES
CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc3nc(nn3c2)-c2c(C)cc(OCCCS(C)(=O)=O)cc2C)cc1
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Compound Formula C31H33N3O6S
Compound Structure
Protein Name
Free fatty acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
EC50 = 117 nM
   TI
   LI
   LO
   TS
2
EC50 = 1490 nM
   TI
   LI
   LO
   TS
3
Ki = 63 nM
   TI
   LI
   LO
   TS