Brief Information of the Compound and Protein
Compound Name
(3S)-3-[4-[(5-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylthiophen-2-yl)methoxy]phenyl]hex-4-ynoic acid
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PubChem ID
CID: 137661294
Canonical SMILES
CC#C[C@@H](CC(O)=O)c1ccc(OCc2ccc(s2)N2CCC3(CCc4ccccc34)CC2)cc1
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Compound Formula C30H31NO3S
Compound Structure
Protein Name
Free fatty acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 8 nM
   TI
   LI
   LO
   TS
2
Ki = 8.2 nM
   TI
   LI
   LO
   TS