Brief Information of the Compound and Protein
Compound Name
 Compound Info 
9-(1-methylpyrazol-4-yl)-1-(1-prop-2-enoyl-2,3-dihydroindol-6-yl)benzo[h][1,6]naphthyridin-2-one
    Show/Hide
 PubChem ID
CID: 71748056
Canonical SMILES
Cn1cc(cn1)-c1ccc2ncc3ccc(=O)n(-c4ccc5CCN(C(=O)C=C)c5c4)c3c2c1
    Show/Hide
Compound Formula C27H21N5O2
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
2
Ki = 14.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM