Brief Information of the Compound and Protein
Compound Name
(E)-3-(4-((6-hydroxy-2- (4- hydroxyphenyl)benzo[b] thiophen-3- yl)oxy)phenyl)-N- methylacrylamide
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PubChem ID
CID: 78323955
Canonical SMILES
CNC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(O)cc2)cc1
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Compound Formula C24H19NO4S
Compound Structure
Protein Name
Estrogen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7 Homo sapiens (Human)  2
1
IC50 = 53 nM
   TI
   LI
   LO
   TS
2
IC50 = 58 nM
   TI
   LI
   LO
   TS