Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[(4S)-3,3-difluoro-4-hydroxypyrrolidin-1-yl]-N-(6-fluoro-1-oxo-2H-isoquinolin-7-yl)thiophene-2-sulfonamide
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 PubChem ID
CID: 121378618
Canonical SMILES
O[C@H]1CN(CC1(F)F)c1ccc(s1)S(=O)(=O)Nc1cc2c(cc[nH]c2=O)cc1F
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Compound Formula C17H14F3N3O4S2
Compound Structure
Protein Name
 Protein Info 
Bifunctional purine biosynthesis protein ATIC
Protein Classification
Enzyme
Uniprot ID
P31939
Gene Name
ATIC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000145 NCI-H460
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 31 nM
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