Brief Information of the Compound and Protein
Compound Name
(6S)-6-benzyl-2-[(3-chlorophenyl)methoxy]-7,9-dihydro-6H-pyrimido[2,1-c][1,4]oxazin-4-one
    Show/Hide
PubChem ID
CID: 137655893
Canonical SMILES
Clc1cccc(COc2cc(=O)n3[C@@H](Cc4ccccc4)COCc3n2)c1
    Show/Hide
Compound Formula C21H19ClN2O3
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 1.1 nM
   TI
   LI
   LO
   TS