Brief Information of the Compound and Protein
Compound Name
3-[[(6R)-6-benzyl-4-oxo-7,9-dihydro-6H-pyrimido[2,1-c][1,4]oxazin-2-yl]oxymethyl]benzonitrile
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PubChem ID
CID: 137635120
Canonical SMILES
O=c1cc(OCc2cccc(c2)C#N)nc2COC[C@@H](Cc3ccccc3)n12
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Compound Formula C22H19N3O3
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 12 nM
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