Brief Information of the Compound and Protein
Compound Name
(6R)-6-benzyl-2-[(6-methylpyridin-2-yl)methoxy]-7,9-dihydro-6H-pyrimido[2,1-c][1,4]oxazin-4-one
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PubChem ID
CID: 137650972
Canonical SMILES
Cc1cccc(COc2cc(=O)n3[C@H](Cc4ccccc4)COCc3n2)n1
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Compound Formula C21H21N3O3
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 27 nM
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