Brief Information of the Compound and Protein
Compound Name
2-[(3-chlorophenyl)methoxy]-7-pyridin-3-yloxypyrido[1,2-a]pyrimidin-4-one
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PubChem ID
CID: 137650553
Canonical SMILES
Clc1cccc(COc2cc(=O)n3cc(Oc4cccnc4)ccc3n2)c1
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Compound Formula C20H14ClN3O3
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 14 nM
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