Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamide
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 PubChem ID
CID: 24737642
SID: 49630901
Canonical SMILES
CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1c1nc(cs1)C(=O)c1ccc(F)cc1
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Compound Formula C26H33FN4O3S
Compound Structure
Protein Name
 Protein Info 
E3 ubiquitin-protein ligase XIAP
Protein Classification
Other cytosolic protein
Uniprot ID
P98170
Gene Name
XIAP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 35 nM
   TI
   LI
   LO
   TS
2
IC50 = 35 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 283 nM
2 IC50 = 30 nM
3 IC50 = 1040 nM
4 IC50 = 1050 nM
5 Kd = 52.7 nM