Brief Information of the Compound and Protein
Compound Name
5-[4-chloro-6-[hydroxy-(3-methylimidazol-4-yl)-[6-(trifluoromethyl)pyridin-3-yl]methyl]-2-methoxyquinolin-3-yl]pyrimidine-2-carbonitrile
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PubChem ID
CID: 118005577
Canonical SMILES
COc1nc2ccc(cc2c(Cl)c1-c1cnc(nc1)C#N)C(O)(c1cncn1C)c1ccc(nc1)C(F)(F)F
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Compound Formula C26H17ClF3N7O2
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 310 nM
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